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Descriptor English: Receptor, Transforming Growth Factor-beta Type I
Descriptor Spanish: Receptor Tipo I de Factor de Crecimiento Transformador beta
Descriptor receptor de tipo I del factor de crecimiento transformante beta
Entry term(s) TGFBR1
cinasa 5 similar al receptor de activina
receptor 1 del factor de crecimiento transformador beta
receptor 1 del factor de crecimiento transformante beta
receptor I del factor de crecimiento transformador beta
receptor I del factor de crecimiento transformante beta
receptor de tipo 1 del factor de crecimiento transformador beta
receptor de tipo I del TGF-beta
receptor de tipo I del factor de crecimiento transformador beta
receptor proteína-cinasa del TGF-beta
receptores de tipo I del TGF beta
receptores de tipo I del TGF-beta
Scope note: Serina-treonina-cinasa transmembranaria que forma un complejo heteromérico con el RECEPTOR DE TIPO II DEL FACTOR DE CRECIMIENTO TRANSFORMANTE BETA para unirse al TGF-BETA y regular diversos procesos fisiológicos y patológicos, tales como la detención del ciclo celular, la PROLIFERACIÓN CELULAR, la DIFERENCIACIÓN CELULAR, la CICATRIZACIÓN DE HERIDAS, la producción de MATRIZ EXTRACELULAR, la inmunosupresión y la ONCOGÉNESIS.
Descriptor Portuguese: Receptor do Fator de Crescimento Transformador beta Tipo I
Descriptor French: Récepteur de type I du facteur de croissance transformant bêta
Entry term(s): Activin Receptor like Kinase 5
Activin Receptor-like Kinase 5
Kinase, TbetaR-I
Receptor, TGF-beta Type I
Serine Threonine Protein Kinase Receptor R4
Serine-Threonine-Protein Kinase Receptor R4
TGF beta Receptor Protein Kinase
TGF beta Type I Receptor
TGF beta Type I Receptors
TGF-beta RPK
TGF-beta Receptor Protein Kinase
TGF-beta Type I Receptor
TGF-beta Type I Receptors
TGFBR1
TbetaR I Kinase
TbetaR-I Kinase
Transforming Growth Factor beta Receptor I
Transforming Growth Factor, beta Receptor 1
Type I TGF beta Receptor
Type I TGF beta Receptors
Type I TGF-beta Receptor
Type I TGF-beta Receptors
Tree number(s): D08.811.913.696.620.682.700.789
D12.776.476.563.789
D12.776.543.750.705.852.720.500
D12.776.543.750.750.400.820.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077293
Scope note: A transmembrane serine-threonine kinase that forms a heteromeric complex with TYPE II TGF-BETA RECEPTORS to bind TGF-BETA and regulate a variety of physiological and pathological processes including CELL CYCLE ARREST; CELL PROLIFERATION; CELL DIFFERENTIATION; WOUND HEALING; EXTRACELLULAR MATRIX production, immunosuppression and ONCOGENESIS.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Registry Number: EC 2.7.11.30
Public MeSH Note: 2019; see TGF-BETA TYPE I RECEPTOR 1995-2018; RECEPTOR, TRANSFORMING GROWTH FACTOR-BETA TYPE I was indexed under PROTEIN-SERINE-THREONINE KINASES and RECEPTORS, TRANSFORMING GROWTH FACTOR BETA 2008-2018; under ACTIVIN RECEPTORS, TYPE I 1994-2018; and under PROTEIN-SERINE-THREONINE KINASES 1994-2001
History Note: 2019 (1994)
DeCS ID: 57593
Unique ID: D000077293
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/27
Receptor, Transforming Growth Factor-beta Type I - Preferred
Concept UI M000640354
Scope note A transmembrane serine-threonine kinase that forms a heteromeric complex with TYPE II TGF-BETA RECEPTORS to bind TGF-BETA and regulate a variety of physiological and pathological processes including CELL CYCLE ARREST; CELL PROLIFERATION; CELL DIFFERENTIATION; WOUND HEALING; EXTRACELLULAR MATRIX production, immunosuppression and ONCOGENESIS.
Preferred term Receptor, Transforming Growth Factor-beta Type I
Entry term(s) Activin Receptor like Kinase 5
Activin Receptor-like Kinase 5
Kinase, TbetaR-I
Receptor, TGF-beta Type I
Serine Threonine Protein Kinase Receptor R4
Serine-Threonine-Protein Kinase Receptor R4
TGF beta Receptor Protein Kinase
TGF beta Type I Receptor
TGF beta Type I Receptors
TGF-beta RPK
TGF-beta Receptor Protein Kinase
TGF-beta Type I Receptor
TGF-beta Type I Receptors
TGFBR1
TbetaR I Kinase
TbetaR-I Kinase
Transforming Growth Factor beta Receptor I
Transforming Growth Factor, beta Receptor 1
Type I TGF beta Receptor
Type I TGF beta Receptors
Type I TGF-beta Receptor
Type I TGF-beta Receptors



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