| Descriptor English: | Von Hippel-Lindau Tumor Suppressor Protein | ||||
| Descriptor Spanish: |
Proteína Supresora de Tumores del Síndrome de Von Hippel-Lindau
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| Descriptor Portuguese: | Proteína Supressora de Tumor Von Hippel-Lindau | ||||
| Descriptor French: | Protéine Von Hippel-Lindau supresseur de tumeur | ||||
| Entry term(s): |
VHL Tumor Suppressor Protein Von Hippel Lindau Tumor Suppressor Protein |
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| Tree number(s): |
D08.811.464.938.750.875 D12.776.624.776.865 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D051794 | ||||
| Scope note: | A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. It is inactivated in VON HIPPEL-LINDAU SYNDROME. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Entry Combination: |
deficiency:von Hippel-Lindau Disease
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| Registry Number: | EC 2.3.2.27 | ||||
| Public MeSH Note: | 2006; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN was indexed under TUMOR SUPPRESSOR PROTEINS 2002-2005, under UBIQUITIN-PROTEIN LIGASES 2004-2005, under LIGASES 2002-3003, under PROTEINS 1995-2001, & under NUCLEAR PROTEINS 1995 |
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| History Note: | 2006 (1995) |
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| DeCS ID: | 50588 | ||||
| Unique ID: | D051794 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 2006/01/01 | ||||
| Date of Entry: | 2005/06/30 | ||||
| Revision Date: | 2016/06/02 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Von Hippel-Lindau Tumor Suppressor Protein
- Preferred
| Concept UI |
M0481855 |
| Scope note | A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. It is inactivated in VON HIPPEL-LINDAU SYNDROME. |
| Preferred term | Von Hippel-Lindau Tumor Suppressor Protein |
| Entry term(s) |
VHL Tumor Suppressor Protein Von Hippel Lindau Tumor Suppressor Protein |
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