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Descriptor English: Replication Protein C
Descriptor Spanish: Proteína de Replicación C
Descriptor proteína de replicación C
Entry term(s) factor C de replicación
Scope note: Proteína de unión al ADN que consta de 5 polipéptidos y desempeña una función importante en la REPLICACIÓN DEL ADN en los eucariotas. Se une a las uniones plantilla del CEBADOR DE ADN y aporta ANTÍGENO NUCLEAR DE CÉLULAS PROLIFERANTES y ADN POLIMERASAS al lugar donde se efectúa la síntesis de ADN.
Descriptor Portuguese: Proteína de Replicação C
Descriptor French: Protéine C de réplication
Entry term(s): Activator 1 Protein
Activator 1 Protein, 145 kDa Subunit
Activator 1 Protein, 36 kDa Subunit
Activator 1 Protein, 37 kDa Subunit
Activator 1 Protein, 38 kDa Subunit
Activator 1 Protein, 40 kDa Subunit
Activator 1 p40
Replication Factor C
Replication Factor C, Subunit 1
Replication Factor C, Subunit 2
Replication Factor C, Subunit 3
Replication Factor C, Subunit 4
Replication Factor C, Subunit 5
Replication Protein C, Subunit 1
Replication Protein C, Subunit 2
Replication Protein C, Subunit 3
Replication Protein C, Subunit 4
Replication Protein C, Subunit 5
Tree number(s): D08.811.277.040.013.500.438
D08.811.277.040.025.024.438
D12.776.157.025.750.438
D12.776.260.702
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051818
Scope note: A DNA-binding protein and AAA ATPase that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. It binds DNA PRIMER-template junctions and recruits PROLIFERATING CELL NUCLEAR ANTIGEN and DNA POLYMERASES to the site of DNA synthesis.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.4.-
Public MeSH Note: 2006; see REPLICATION FACTOR C 2006, REPLICATION PROTEIN C was indexed under DNA-BINDING PROTEINS 1992-2005
History Note: 2006(1992)
DeCS ID: 51055
Unique ID: D051818
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/03/01
Replication Protein C - Preferred
Concept UI M0199689
Scope note A DNA-binding protein and AAA ATPase that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. It binds DNA PRIMER-template junctions and recruits PROLIFERATING CELL NUCLEAR ANTIGEN and DNA POLYMERASES to the site of DNA synthesis.
Preferred term Replication Protein C
Entry term(s) Activator 1 Protein
Replication Factor C
Replication Protein C, Subunit 4 - Narrower
Concept UI M0359016
Preferred term Replication Protein C, Subunit 4
Entry term(s) Activator 1 Protein, 37 kDa Subunit
Replication Factor C, Subunit 4
Replication Protein C, Subunit 2 - Narrower
Concept UI M0199685
Preferred term Replication Protein C, Subunit 2
Entry term(s) Activator 1 Protein, 40 kDa Subunit
Activator 1 p40
Replication Factor C, Subunit 2
Replication Protein C, Subunit 1 - Narrower
Concept UI M0481935
Preferred term Replication Protein C, Subunit 1
Entry term(s) Activator 1 Protein, 145 kDa Subunit
Replication Factor C, Subunit 1
Replication Protein C, Subunit 3 - Narrower
Concept UI M0359015
Preferred term Replication Protein C, Subunit 3
Entry term(s) Activator 1 Protein, 38 kDa Subunit
Replication Factor C, Subunit 3
Replication Protein C, Subunit 5 - Narrower
Concept UI M0359017
Preferred term Replication Protein C, Subunit 5
Entry term(s) Activator 1 Protein, 36 kDa Subunit
Replication Factor C, Subunit 5



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