| Descriptor English: | Myotonin-Protein Kinase | ||||||
| Descriptor Spanish: |
Proteína Quinasa de Distrofia Miotónica
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| Descriptor Portuguese: | Miotonina Proteína Quinase | ||||||
| Descriptor French: | Myotonin-protein kinase | ||||||
| Entry term(s): |
DM Kinase DM Protein Kinase DM-Kinase DM1PK Protein DMPK Protein Kinase, DM Protein Kinase, Myotonin-Protein MDGP Protein MDPK Protein Myotonic Dystrophy Protein Kinase Myotonin Protein Kinase Protein Kinase, DM Protein, DM1PK Protein, DMPK Protein, MDGP Protein, MDPK |
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| Tree number(s): |
D08.811.913.696.620.682.700.576 D12.776.476.563.576 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D065636 | ||||||
| Scope note: | Serine/threonine protein kinase responsible for various SKELETAL MUSCLE functions; HEART CONDUCTION SYSTEM activity; calcium HOMEOSTASIS; calcium uptake by SARCOPLASMIC RETICULUM and SYNAPTIC PLASTICITY. It is encoded by the DMPK gene and its abnormal EXPANDED TRINUCLEOTIDE REPEAT of CTG in the 3'-UTR is associated with MYOTONIC DYSTROPHY 1. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.1 | ||||||
| Public MeSH Note: | 2015 |
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| History Note: | 2015 |
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| Related: |
Myotonic Dystrophy
MeSH | ||||||
| DeCS ID: | 55613 | ||||||
| Unique ID: | D065636 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2015/01/01 | ||||||
| Date of Entry: | 2014/06/26 | ||||||
| Revision Date: | 2014/06/11 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Myotonin-Protein Kinase
- Preferred
| Concept UI |
M0590267 |
| Scope note | Serine/threonine protein kinase responsible for various SKELETAL MUSCLE functions; HEART CONDUCTION SYSTEM activity; calcium HOMEOSTASIS; calcium uptake by SARCOPLASMIC RETICULUM and SYNAPTIC PLASTICITY. It is encoded by the DMPK gene and its abnormal EXPANDED TRINUCLEOTIDE REPEAT of CTG in the 3'-UTR is associated with MYOTONIC DYSTROPHY 1. |
| Preferred term | Myotonin-Protein Kinase |
| Entry term(s) |
DM Kinase DM Protein Kinase DM-Kinase DM1PK Protein DMPK Protein Kinase, DM Protein Kinase, Myotonin-Protein MDGP Protein MDPK Protein Myotonic Dystrophy Protein Kinase Myotonin Protein Kinase Protein Kinase, DM Protein, DM1PK Protein, DMPK Protein, MDGP Protein, MDPK |
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