| Descriptor English: | BRCA2 Protein | ||||||
| Descriptor Spanish: |
Proteína BRCA2
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| Descriptor Portuguese: | Proteína BRCA2 | ||||||
| Descriptor French: | Protéine BRCA2 | ||||||
| Entry term(s): |
BRCA2 Gene Product Breast Cancer 2 Gene Product Breast Cancer 2 Protein FANCD1 Protein Fanconi Anemia Complementation Group D1 Protein Fanconi Anemia Group D1 Complementing Protein Fanconi Anemia Group D1 Protein |
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| Tree number(s): |
D12.776.313.249 D12.776.624.776.101 D12.776.660.105 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D024682 | ||||||
| Scope note: | A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6) |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Neoplasm Proteins (1995-2001) Transcription Factors (1995-2001) |
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| Public MeSH Note: | 2002; BCRA2 PROTEIN was indexed under NEOPLASM PROTEINS & TRANSCRIPTION FACTORS 1995-2001 |
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| History Note: | 2002; use BRCA2 PROTEIN (NM) 1995-2001 |
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| Related: |
Hereditary Breast and Ovarian Cancer Syndrome
MeSH | ||||||
| DeCS ID: | 36228 | ||||||
| Unique ID: | D024682 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2002/01/01 | ||||||
| Date of Entry: | 2001/07/25 | ||||||
| Revision Date: | 2011/06/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
|
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BRCA2 Protein
- Preferred
| Concept UI |
M0242709 |
| Scope note | A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6) |
| Preferred term | BRCA2 Protein |
| Entry term(s) |
BRCA2 Gene Product Breast Cancer 2 Gene Product Breast Cancer 2 Protein FANCD1 Protein Fanconi Anemia Complementation Group D1 Protein Fanconi Anemia Group D1 Complementing Protein Fanconi Anemia Group D1 Protein |
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