| Descriptor English: | Janus Kinase 2 | ||||||
| Descriptor Spanish: |
Janus Quinasa 2
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| Descriptor Portuguese: | Janus Quinase 2 | ||||||
| Descriptor French: | Kinase Janus-2 | ||||||
| Entry term(s): |
JAK 2 Protein Tyrosine Kinase JAK-2 Protein Tyrosine Kinase JAK2 Protein Tyrosine Kinase |
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| Tree number(s): |
D08.811.913.696.620.682.725.124.200 D12.776.476.568.124.200 D12.776.624.664.700.117 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D053614 | ||||||
| Scope note: | A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPTORS; and a variety of CYTOKINE RECEPTORS such as ERYTHROPOIETIN RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of Janus kinase 2 due to GENETIC TRANSLOCATIONS have been associated with a variety of MYELOPROLIFERATIVE DISORDERS. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.10.2 | ||||||
| Public MeSH Note: | 2007; JANUS KINASE 2 was indexed under PROTEIN-TYROSINE KINASE & PROTO-ONCOGENE PROTEINS 1992-2006 |
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| History Note: | 2007(1992) |
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| Related: |
src Homology Domains
MeSH | ||||||
| DeCS ID: | 52254 | ||||||
| Unique ID: | D053614 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2007/01/01 | ||||||
| Date of Entry: | 2006/07/05 | ||||||
| Revision Date: | 2015/11/23 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Janus Kinase 2
- Preferred
| Concept UI |
M0203030 |
| Scope note | A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPTORS; and a variety of CYTOKINE RECEPTORS such as ERYTHROPOIETIN RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of Janus kinase 2 due to GENETIC TRANSLOCATIONS have been associated with a variety of MYELOPROLIFERATIVE DISORDERS. |
| Preferred term | Janus Kinase 2 |
| Entry term(s) |
JAK 2 Protein Tyrosine Kinase JAK-2 Protein Tyrosine Kinase JAK2 Protein Tyrosine Kinase |
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