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Descriptor English: Zinc Finger Protein GLI1
Descriptor Spanish: Proteína con Dedos de Zinc GLI1
Descriptor proteína con dedos de zinc GLI1
Entry term(s) proteína Gli
proteína Gli1
proteína del oncogén GLI
proteína del oncogén asociada a glioma
proteína del oncogén asociado a glioma
Scope note: Activador transcripcional y proteína oncogénica que contiene dos DEDOS DE ZINC CYS2-HIS2. Se expresan dos isoformas; ambas regulan la expresión de genes específicos durante el desarrollo de los rasgos craneofaciales, los dedos, el SISTEMA NERVIOSO CENTRAL y el TRACTO GASTROINTESTINAL. También regulan la señalización de la PROTEÍNA SONIC HEDGEHOG y la proliferación celular.
Descriptor Portuguese: Proteína GLI1 em Dedos de Zinco
Descriptor French: Protéine à doigt de zinc GLI1
Entry term(s): GLI Protein, Oncogene
Gli Protein
Gli1 Protein
Glioma Associated Oncogene Protein
Glioma-Associated Oncogene Protein
Oncogene GLI Protein
Oncogene Protein, Glioma-Associated
Tree number(s): D12.776.260.755.850
D12.776.624.664.700.989
D12.776.930.900.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071676
Scope note: A transcriptional activator and oncogene protein that contains two CYS2-HIS2 ZINC FINGERS. Two isoforms are expressed; both regulate the expression of specific genes during development of craniofacial features, digits, the CENTRAL NERVOUS SYSTEM; and the GASTROINTESTINAL TRACT. They also regulate SONIC HEDGEHOG PROTEIN signaling and cell proliferation.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2017; ZINC FINGER PROTEIN GLI1 was indexed under TRANS-ACTIVATORS and ONCOGENE PROTEINS 2006-2016 and under TRANSCRIPTION FACTORS 1993-2006
History Note: 2017 (1993)
DeCS ID: 56611
Unique ID: D000071676
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/04/15
Zinc Finger Protein GLI1 - Preferred
Concept UI M000615302
Scope note A transcriptional activator and oncogene protein that contains two CYS2-HIS2 ZINC FINGERS. Two isoforms are expressed; both regulate the expression of specific genes during development of craniofacial features, digits, the CENTRAL NERVOUS SYSTEM; and the GASTROINTESTINAL TRACT. They also regulate SONIC HEDGEHOG PROTEIN signaling and cell proliferation.
Preferred term Zinc Finger Protein GLI1
Entry term(s) GLI Protein, Oncogene
Gli Protein
Gli1 Protein
Glioma Associated Oncogene Protein
Glioma-Associated Oncogene Protein
Oncogene GLI Protein
Oncogene Protein, Glioma-Associated



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