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Descriptor English: Cyclins
Descriptor Spanish: Ciclinas
Descriptor ciclinas
Scope note: Proteínas reguladoras que funcionan en el ciclo celular para activar el factor promotor de la maduración. Forman complejos con p34cdc2 (PROTEÍNA P34CDC2), la subunidad catalítica del FACTOR PROMOTOR DE LA MADURACIÓN y modulan su actividad de proteína cinasa. Las propias ciclinas no tienen actividad enzimática.
Descriptor Portuguese: Ciclinas
Descriptor French: Cyclines
Entry term(s): Cycline
Tree number(s): D12.644.360.262
D12.776.167.218
D12.776.476.262
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016213
Scope note: A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME ACTIVATORS that drive the CELL CYCLE through transitions between phases. A subset of cyclins may also function as transcriptional regulators.
Annotation: note specifics
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
Related: Facteur de promotion de la maturation MeSH
DeCS ID: 30942
Unique ID: D016213
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/06/17
Revision Date: 2015/11/23
Cyclines - Preferred
Concept UI M0024762
Preferred term Cyclines
Entry term(s) Cycline



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