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Descriptor in English: Kallikreins
Descriptor in Spanish: Calicreínas
Descriptor in Portuguese: Calicreínas
Descriptor in French: Kallicréines
Entry term(s): Callicrein
Dilminal
Enzyme, Kinin-Forming
Kallidinogenase
Kalliginogenase
Kallikrein
Kallikrein A
Kallikrein B'
Kallikrein Light Chain
Kinin Forming Enzyme
Kinin-Forming Enzyme
Kininogenase
Light Chain, Kallikrein
Padutin
alpha Kallikrein
alpha-Kallikrein
beta Kallikrein
beta Kallikrein B
beta-Kallikrein
beta-Kallikrein B
Tree number(s): D08.811.277.656.300.760.442
D08.811.277.656.959.350.442
D12.776.124.125.597
D23.119.597
Scope note: Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifically, Kallikreins are potent vasodilators and hypotensives and increase vascular permeability and affect smooth muscle. They act as infertility agents in men. Three forms are recognized, PLASMA KALLIKREIN (EC 3.4.21.34), TISSUE KALLIKREIN (EC 3.4.21.35), and PROSTATE-SPECIFIC ANTIGEN (EC 3.4.21.77).
Annotation: /antag permitted but consider KALLIKREIN-TRYPSIN INACTIVATOR
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 2000(1963)
See also the descriptors: Coagulants MeSH
DeCS UI: 23326
Descriptor UI: D007610
Date Established: 2000/01/01
Date of Entry: 1999/01/01
Revision Date: 2009/07/06
Kallikreins - Preferred
Concept UI M0011897
Scope note Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifically, Kallikreins are potent vasodilators and hypotensives and increase vascular permeability and affect smooth muscle. They act as infertility agents in men. Three forms are recognized, PLASMA KALLIKREIN (EC 3.4.21.34), TISSUE KALLIKREIN (EC 3.4.21.35), and PROSTATE-SPECIFIC ANTIGEN (EC 3.4.21.77).
Preferred term Kallikreins
Entry term(s) Callicrein
Enzyme, Kinin-Forming
Kallidinogenase
Kalliginogenase
Kallikrein
Kinin Forming Enzyme
Kinin-Forming Enzyme
Kininogenase
Kallikrein Light Chain - Narrower
Concept UI M0011902
Preferred term Kallikrein Light Chain
Entry term(s) Light Chain, Kallikrein
Padutin - Narrower
Concept UI M0332548
Preferred term Padutin
Kallikrein A - Narrower
Concept UI M0011898
Preferred term Kallikrein A
beta-Kallikrein - Narrower
Concept UI M0011895
Preferred term beta-Kallikrein
Entry term(s) beta Kallikrein
beta-Kallikrein B - Narrower
Concept UI M0011896
Preferred term beta-Kallikrein B
Entry term(s) beta Kallikrein B
Dilminal - Narrower
Concept UI M0332549
Preferred term Dilminal
Kallikrein B' - Narrower
Concept UI M0011899
Preferred term Kallikrein B'
alpha-Kallikrein - Narrower
Concept UI M0011894
Preferred term alpha-Kallikrein
Entry term(s) alpha Kallikrein



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