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Descriptor in English: Cyclins
Descriptor in Spanish: Ciclinas
Descriptor in Portuguese: Ciclinas
Descriptor in French: Cyclines
Entry term(s): Cyclin
Tree number(s): D12.644.360.262
D12.776.167.218
D12.776.476.262
Scope note: A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME ACTIVATORS that drive the CELL CYCLE through transitions between phases. A subset of cyclins may also function as transcriptional regulators.
Annotation: note specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Online Note: use CYCLINS to search CYCLIN 1991-2
History Note: 93; was CYCLIN 1991-2
See also the descriptors: Maturation-Promoting Factor MeSH
DeCS UI: 30942
Descriptor UI: D016213
Date Established: 1991/01/01
Date of Entry: 1990/06/17
Revision Date: 2015/11/23
Cyclins - Preferred
Concept UI M0024762
Scope note A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME ACTIVATORS that drive the CELL CYCLE through transitions between phases. A subset of cyclins may also function as transcriptional regulators.
Preferred term Cyclins
Entry term(s) Cyclin



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