| Descriptor English: | Proto-Oncogene Proteins c-bcl-2 | ||||||
| Descriptor Spanish: |
Proteínas Proto-Oncogénicas c-bcl-2
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| Descriptor Portuguese: | Proteínas Proto-Oncogênicas c-bcl-2 | ||||||
| Descriptor French: | Protéines proto-oncogènes c-bcl-2 | ||||||
| Entry term(s): |
B Cell Leukemia 2 Family Proteins B-Cell Leukemia 2 Family Proteins BCL2 Family Proteins BCL2 Proteins Family Proteins, BCL2 Proteins, BCL2 Proteins, BCL2 Family Proto Oncogene Proteins c bcl 2 Proto-Oncogene Proteins, bcl-2 bcl 2 Proto Oncogene Proteins bcl-2 Proto-Oncogene Proteins c bcl 2 Proteins c-bcl-2 Proteins c-bcl-2, Proto-Oncogene Proteins |
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| Tree number(s): |
D12.644.360.075.718 D12.776.476.075.718 D12.776.624.664.700.169 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D019253 | ||||||
| Scope note: | Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Proto-Oncogene Proteins (1989-1996) |
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| Public MeSH Note: | 97; PROTO-ONCOGENE PROTEIN BCL-2 was indexed under PROTO-ONCOGENE PROTEINS 1989-96 |
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| Online Note: | use PROTO-ONCOGENE PROTEINS C-BCL-2 (NM) to search PROTO-ONCOGENE PROTEIN BCL-2 1989-96 |
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| History Note: | 97; was PROTO-ONCOGENE PROTEIN BCL-2 (NM) 1989-96 |
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| DeCS ID: | 33061 | ||||||
| Unique ID: | D019253 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1997/01/01 | ||||||
| Date of Entry: | 1996/06/10 | ||||||
| Revision Date: | 2015/11/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Proto-Oncogene Proteins c-bcl-2
- Preferred
B-Cell Leukemia 2 Family Proteins
- Broader
| Concept UI |
M0028673 |
| Scope note | Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma. |
| Preferred term | Proto-Oncogene Proteins c-bcl-2 |
| Entry term(s) |
Proto Oncogene Proteins c bcl 2 Proto-Oncogene Proteins, bcl-2 bcl 2 Proto Oncogene Proteins bcl-2 Proto-Oncogene Proteins c bcl 2 Proteins c-bcl-2 Proteins c-bcl-2, Proto-Oncogene Proteins |
| Concept UI |
M0480025 |
| Preferred term | B-Cell Leukemia 2 Family Proteins |
| Entry term(s) |
B Cell Leukemia 2 Family Proteins BCL2 Family Proteins BCL2 Proteins Family Proteins, BCL2 Proteins, BCL2 Proteins, BCL2 Family |
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