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Descriptor English: beta Catenin
Descriptor Spanish: beta Catenina
Descriptor beta catenina
Entry term(s) catenina beta
Scope note: Catenina multifuncional que participa en la ADHESIÓN CELULAR y en la señalización nuclear. La beta catenina se une a CADHERINAS y favorece la unión de sus colas citoplásmicas a la ACTINA en el CITOESQUELETO por medio de la ALFA CATENINA. Sirve también como coactivador transcripcional y componente en dirección anterógrada de las VÍAS DE TRANSDUCCIÓN DE SEÑALES mediadas por la PROTEÍNA WNT.
Descriptor Portuguese: beta Catenina
Descriptor French: bêta-Caténine
Entry term(s): Catenin, beta
beta-Catenin
Tree number(s): D12.776.091.249
D12.776.220.145.500
D12.776.930.130
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051176
Scope note: A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; BETA CATENIN was indexed under CYTOSKELETAL PROTEINS & TRANS-ACTIVATORS 1993-2005, & under CADHERINS 1992
History Note: 2006(1992)
DeCS ID: 50821
Unique ID: D051176
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
beta Catenin - Preferred
Concept UI M0195076
Scope note A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.
Preferred term beta Catenin
Entry term(s) Catenin, beta
beta-Catenin



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