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Descriptor English: Death Domain Receptor Signaling Adaptor Proteins
Descriptor Spanish: Proteínas Adaptadoras de Señalización del Receptor del Dominio de Muerte
Descriptor proteínas adaptadoras de señalización de receptores de dominios de muerte
Scope note: Proteínas adaptadoras de la señalización intracelular que contienen DOMINIOS EFECTORES DE MUERTE y se unen a la región del DOMINIO DE MUERTE citoplasmática que se encuentra en los RECEPTORES DE DOMINIOS DE MUERTE. Muchas de las proteínas de esta clase participan en la señalización intracelular que implica a RECEPTORES DEL FACTOR DE NECROSIS TUMORAL.
Descriptor Portuguese: Proteínas Adaptadoras de Sinalização de Receptores de Domínio de Morte
Descriptor French: Protéines adaptatrices de signalisation des récepteurs à domaine de mort
Entry term(s): DED Signaling Adaptor Proteins
DISC (Death Inducing Signaling Complex)
Death Effector Domain Containing Proteins
Death Effector Domain Signaling Adaptor Proteins
Death Inducing Signaling Complex Proteins
Fas DISC Components
Fas-DISC Components
fas Death Inducing Signaling Complex Components
fas Death-Inducing Signaling Complex Components
Tree number(s): D12.644.360.024.285
D12.644.360.075.421
D12.776.157.057.018
D12.776.476.024.320
D12.776.476.075.421
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053418
Scope note: Intracellular signaling adaptor proteins that contain DEATH EFFECTOR DOMAINS and bind to the cytoplasmic DEATH DOMAIN region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling involving TUMOR NECROSIS FACTOR RECEPTORS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2007; DISC (DEATH INDUCING SIGNALING COMPLEX) was indexed under TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS 2006 & and under RECEPTORS, TUMOR NECROSIS FACTORS 2002-2006
History Note: 2007(2002)
Related: Death Effector Domain MeSH
DeCS ID: 52308
Unique ID: D053418
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/05/24
Death Domain Receptor Signaling Adaptor Proteins - Preferred
Concept UI M0492979
Scope note Intracellular signaling adaptor proteins that contain DEATH EFFECTOR DOMAINS and bind to the cytoplasmic DEATH DOMAIN region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling involving TUMOR NECROSIS FACTOR RECEPTORS.
Preferred term Death Domain Receptor Signaling Adaptor Proteins
Entry term(s) DED Signaling Adaptor Proteins
Death Effector Domain Signaling Adaptor Proteins
Death Inducing Signaling Complex Proteins
Death Effector Domain Containing Proteins - Related but not broader or narrower
Concept UI M000610855
Preferred term Death Effector Domain Containing Proteins
fas Death-Inducing Signaling Complex Components - Narrower
Concept UI M0492984
Preferred term fas Death-Inducing Signaling Complex Components
Entry term(s) Fas DISC Components
Fas-DISC Components
fas Death Inducing Signaling Complex Components
DISC (Death Inducing Signaling Complex) - Related but not broader or narrower
Concept UI M0444186
Preferred term DISC (Death Inducing Signaling Complex)



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