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Descriptor English: Xeroderma Pigmentosum Group A Protein
Descriptor Spanish: Proteína de la Xerodermia Pigmentosa del Grupo A
Descriptor proteína de la xerodermia pigmentosa del grupo A
Entry term(s) proteína del xeroderma pigmentoso del grupo A
Scope note: Proteína MOTIVO DEDO DE ZINC que reconoce el ADN dañado e interacciona con él. Se trata de una proteína de unión al ADN que desempeña un papel esencial en el proceso de REPARACIÓN DEL ADN. Las mutaciones en esta proteína se asocian a las formas más graves de XERODERMIA PIGMENTOSA.
Descriptor Portuguese: Proteína de Xeroderma Pigmentoso Grupo A
Descriptor French: Protéine XPA
Entry term(s): Protéine de réparation XPA
Protéine du groupe A de Xeroderma Pigmentosum
Tree number(s): D12.776.157.687.875
D12.776.260.975
D12.776.660.720.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051760
Scope note: A ZINC FINGER MOTIF protein that recognizes and interacts with damaged DNA. It is a DNA-binding protein that plays an essential role in NUCLEOTIDE EXCISION REPAIR. Mutations in this protein are associated with the most severe form of XERODERMA PIGMENTOSUM.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
Entry Combination: deficiency:Xeroderma Pigmentosum
DeCS ID: 51066
Unique ID: D051760
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/06/29
Protéine XPA - Preferred
Concept UI M0182049
Preferred term Protéine XPA
Entry term(s) Protéine de réparation XPA
Protéine du groupe A de Xeroderma Pigmentosum



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