Descriptor English: | Retinoblastoma-Like Protein p130 | ||||||
Descriptor Spanish: |
Proteína p130 Similar a la del Retinoblastoma
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Descriptor Portuguese: | Proteína p130 Retinoblastoma-Like | ||||||
Descriptor French: | Protéine p130 de type rétinoblastome | ||||||
Entry term(s): |
RBL2 Protein Retinoblastoma Like Protein 2 Retinoblastoma Like Protein p130 Retinoblastoma-Like Protein 2 p130, Retinoblastoma-Like Protein |
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Tree number(s): |
D12.776.624.776.735 D12.776.660.794 D12.776.744.755 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050717 | ||||||
Scope note: | A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and E2F5 TRANSCRIPTION FACTOR. RBL2 also interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Public MeSH Note: | 2006; RETINOBLASTOMA-LIKE PROTEIN P130 was indexed under PROTEIN 2004-2005, under ADAPTOR PROTEINS 2004, under PHOSPHOPROTEINS 1996-2004, & under PROTEINS 1994-1995 |
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History Note: | 2006(1994) |
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DeCS ID: | 51163 | ||||||
Unique ID: | D050717 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2006/01/01 | ||||||
Date of Entry: | 2005/06/30 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
|
Retinoblastoma-Like Protein p130
- Preferred
Concept UI |
M0477275 |
Scope note | A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and E2F5 TRANSCRIPTION FACTOR. RBL2 also interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS. |
Preferred term | Retinoblastoma-Like Protein p130 |
Entry term(s) |
RBL2 Protein Retinoblastoma Like Protein 2 Retinoblastoma Like Protein p130 Retinoblastoma-Like Protein 2 p130, Retinoblastoma-Like Protein |
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