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Descriptor English: Stathmin
Descriptor Spanish: Estatmina
Descriptor Portuguese: Estatmina
Descriptor French: Stathmine
Entry term(s): Alpha Stathmin
Alpha-Stathmin
Beta Stathmin
Beta-Stathmin
Lap18 Protein
Leukemia Associated Phosphoprotein p18
Leukemia-Associated Phosphoprotein p18
Metablastin
Oncoprotein 18
Op18 Phosphoprotein
Op18a Protein
Op18b Protein
Phosphoprotein p18
Phosphoprotein p19
Phosphoprotein, Op18
Prosolin
p18, Leukemia-Associated Phosphoprotein
p18, Phosphoprotein
p19, Phosphoprotein
Tree number(s): D12.776.220.600.450.480
D12.776.624.664.700.957
D12.776.744.772
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050777
Scope note: A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; STATHMIN was indexed under MICROTUBULE PROTEINS & PHOSPHOPROTEINS 1987-2005
History Note: 2006(1987)
DeCS ID: 50938
Unique ID: D050777
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Stathmin - Preferred
Concept UI M0166763
Scope note A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.
Preferred term Stathmin
Entry term(s) Lap18 Protein
Leukemia Associated Phosphoprotein p18
Leukemia-Associated Phosphoprotein p18
Metablastin
Oncoprotein 18
Op18 Phosphoprotein
Phosphoprotein p18
Phosphoprotein p19
Phosphoprotein, Op18
Prosolin
p18, Leukemia-Associated Phosphoprotein
p18, Phosphoprotein
p19, Phosphoprotein
Beta-Stathmin - Narrower
Concept UI M0166754
Preferred term Beta-Stathmin
Entry term(s) Beta Stathmin
Op18b Protein
Alpha-Stathmin - Narrower
Concept UI M0166753
Preferred term Alpha-Stathmin
Entry term(s) Alpha Stathmin
Op18a Protein



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