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Descriptor English: Tristetraprolin
Descriptor Spanish: Tristetraprolina
Descriptor tristetraprolina
Scope note: MOTIVO DEDO DE ZINC que contiene un factor de transcripción originalmente identificado como una de las PROTEÍNAS INMEDIATAS TEMPRANAS. Conecta el CITOPLASMA con el NÚCLEO CELULAR y está involucrado en la desestabilización de ARNm por el FACTOR DE NECROSIS TUMORAL ALFA.
Descriptor Portuguese: Tristetraprolina
Descriptor French: Tristétraproline
Entry term(s): G0 G1 Switch Regulatory Protein 24
G0-G1 Switch Regulatory Protein 24
Tristetraprolin Protein
Zinc Finger Protein 36
Tree number(s): D12.776.260.790
D12.776.460.762
D12.776.930.960
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051816
Scope note: A ZINC FINGER MOTIF containing transcription factor that was originally identified as one of the IMMEDIATE-EARLY PROTEINS. It shuttles between the CYTOPLASM and the CELL NUCLEUS and is involved in destabilization of mRNAs for TUMOR NECROSIS FACTOR-ALPHA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; TRISTETRAPROLIN was indexed under DNA-BINDING PROTEINS 2001-2005, & under IMMEDIATE-EARLY PROTEINS 1991-2005, & under PROTEINS 1998-2000
History Note: 2006(1991)
DeCS ID: 51063
Unique ID: D051816
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2005/07/21
Tristetraprolin - Preferred
Concept UI M0184858
Scope note A ZINC FINGER MOTIF containing transcription factor that was originally identified as one of the IMMEDIATE-EARLY PROTEINS. It shuttles between the CYTOPLASM and the CELL NUCLEUS and is involved in destabilization of mRNAs for TUMOR NECROSIS FACTOR-ALPHA.
Preferred term Tristetraprolin
Entry term(s) G0 G1 Switch Regulatory Protein 24
G0-G1 Switch Regulatory Protein 24
Tristetraprolin Protein
Zinc Finger Protein 36



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