| Descriptor English: | Proto-Oncogene Proteins c-mdm2 | ||||||
| Descriptor Spanish: |
Proteínas Proto-Oncogénicas c-mdm2
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| Descriptor Portuguese: | Proteínas Proto-Oncogênicas c-mdm2 | ||||||
| Descriptor French: | Protéines proto-oncogènes c-mdm2 | ||||||
| Entry term(s): |
Double Minute 2 Protein MDMX Protein Mdm 2 Protein Mdm-2 Protein Mdm2 Protein Murine Double Minute 2 Protein Proto Oncogene Proteins c mdm2 Proto-Oncogene Protein, c-mdm2 c mdm2 Proto Oncogene Protein c-mdm2 Proto-Oncogene Protein c-mdm2, Proto-Oncogene Proteins |
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| Tree number(s): |
D08.811.464.938.750.562 D12.776.624.664.700.185 D12.776.660.764 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D051736 | ||||||
| Scope note: | An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.3.2.27 | ||||||
| Public MeSH Note: | 2006; PROTO-ONCOGENE PROTEINS C-MDM2 was indexed under PROTO-ONCOGENE PROTEINS 2005, & under NUCLEAR PROTEINS 1991-2005, & under NEOPLASM PROTEINS 1991-2004 |
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| History Note: | 2006(1991) |
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| DeCS ID: | 50587 | ||||||
| Unique ID: | D051736 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 | ||||||
| Revision Date: | 2016/06/02 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Proto-Oncogene Proteins c-mdm2
- Preferred
| Concept UI |
M0187954 |
| Scope note | An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF. |
| Preferred term | Proto-Oncogene Proteins c-mdm2 |
| Entry term(s) |
Double Minute 2 Protein MDMX Protein Mdm 2 Protein Mdm-2 Protein Mdm2 Protein Murine Double Minute 2 Protein Proto Oncogene Proteins c mdm2 Proto-Oncogene Protein, c-mdm2 c mdm2 Proto Oncogene Protein c-mdm2 Proto-Oncogene Protein c-mdm2, Proto-Oncogene Proteins |
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