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| Descriptor English: | I-kappa B Proteins | ||||||
| Descriptor Spanish: |
Proteínas I-kappa B
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| Descriptor Portuguese: | Proteínas I-kappa B | ||||||
| Descriptor French: | Protéines I-kappa B | ||||||
| Entry term(s): |
I kappa B I kappa B Proteins I-kappa B IkB DNA Binding Proteins IkB DNA-Binding Proteins |
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| Tree number(s): |
D12.644.360.365 D12.776.260.420 D12.776.476.381 D12.776.930.326 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D020672 | ||||||
| Scope note: | A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
DNA-Binding Proteins (1998-1999) Proto-Oncogene Proteins (1993-1998) |
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| Public MeSH Note: | 2000; see I KAPPA B 2000-2005, I KAPPA B PROTEINS was indexed under PROTO-ONCOGENE PROTEINS 1993-1998 & DNA-BINDING PROTEINS 1998-1999 |
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| History Note: | 2006(2000) |
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| Related: |
I-kappa B Kinase
MeSH NF-kappa B MeSH Proto-Oncogene Proteins c-rel MeSH | ||||||
| DeCS ID: | 34471 | ||||||
| Unique ID: | D020672 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2000/01/01 | ||||||
| Date of Entry: | 1999/11/04 | ||||||
| Revision Date: | 2017/06/30 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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I-kappa B Proteins
- Preferred
| Concept UI |
M0328543 |
| Scope note | A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus. |
| Preferred term | I-kappa B Proteins |
| Entry term(s) |
I kappa B I kappa B Proteins I-kappa B IkB DNA Binding Proteins IkB DNA-Binding Proteins |
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